Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_02_ATM_minus_versus_BT_ATM_minus.phenotype_ATM_minus_versus_BT_ATM_minus.cls #ATM_minus_versus_BT_ATM_minus.phenotype_ATM_minus_versus_BT_ATM_minus.cls #ATM_minus_versus_BT_ATM_minus_repos |
| Phenotype | phenotype_ATM_minus_versus_BT_ATM_minus.cls#ATM_minus_versus_BT_ATM_minus_repos |
| Upregulated in class | BT_ATM_minus |
| GeneSet | NCI_CASPASE CASCADE IN APOPTOSIS |
| Enrichment Score (ES) | -0.5225157 |
| Normalized Enrichment Score (NES) | -1.7532938 |
| Nominal p-value | 0.001858736 |
| FDR q-value | 0.11350831 |
| FWER p-Value | 0.865 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | PARP1 | 1422502_at 1422503_s_at 1435368_a_at 1443573_at | 179 | 5.231 | 0.0402 | No | ||
| 2 | CYCS | 1422484_at 1445484_at | 311 | 4.490 | 0.0757 | No | ||
| 3 | BAX | 1416837_at | 554 | 3.775 | 0.0996 | No | ||
| 4 | VIM | 1438118_x_at 1450641_at 1456292_a_at | 965 | 3.024 | 0.1088 | No | ||
| 5 | CASP8 | 1424552_at | 1277 | 2.700 | 0.1196 | No | ||
| 6 | BID | 1417045_at 1447873_x_at 1448560_at | 1558 | 2.443 | 0.1294 | No | ||
| 7 | LMNB2 | 1451849_a_at | 3455 | 1.583 | 0.0574 | No | ||
| 8 | LRDD | 1421397_a_at | 3745 | 1.496 | 0.0580 | No | ||
| 9 | TNF | 1419607_at | 5329 | 1.099 | -0.0041 | No | ||
| 10 | DIABLO | 1417683_at 1425768_at | 6777 | 0.835 | -0.0625 | No | ||
| 11 | CASP1 | 1449265_at | 6797 | 0.832 | -0.0557 | No | ||
| 12 | LMNB1 | 1423520_at 1423521_at | 8697 | 0.521 | -0.1376 | No | ||
| 13 | CASP3 | 1426165_a_at 1430192_at 1449839_at | 9681 | 0.373 | -0.1791 | No | ||
| 14 | BCL2 | 1422938_at 1427818_at 1437122_at 1440770_at 1443837_x_at 1457687_at | 10517 | 0.241 | -0.2150 | No | ||
| 15 | LIMK1 | 1417627_a_at 1425836_a_at 1456234_at 1458989_at | 11665 | 0.066 | -0.2668 | No | ||
| 16 | CASP4 | 1449591_at | 11670 | 0.066 | -0.2663 | No | ||
| 17 | RIPK1 | 1419508_at 1439273_at 1449485_at | 12208 | -0.017 | -0.2907 | No | ||
| 18 | LMNA | 1421654_a_at 1425472_a_at 1426868_x_at 1452212_at 1457670_s_at | 12432 | -0.058 | -0.3004 | No | ||
| 19 | CRADD | 1427505_a_at 1443430_at | 13107 | -0.175 | -0.3295 | No | ||
| 20 | PTK2 | 1423059_at 1430827_a_at 1439198_at 1440082_at 1441475_at 1443384_at 1445137_at | 13566 | -0.252 | -0.3481 | No | ||
| 21 | NUMA1 | 1423974_at 1423975_s_at 1441090_at 1444576_at 1444577_x_at | 13832 | -0.297 | -0.3575 | No | ||
| 22 | GSN | 1415812_at 1436991_x_at 1437171_x_at 1441225_at 1456312_x_at 1456568_at 1456569_x_at | 14015 | -0.327 | -0.3628 | No | ||
| 23 | APP | 1420621_a_at 1427442_a_at 1438373_at 1438374_x_at 1444705_at 1447347_at 1458525_at | 14068 | -0.338 | -0.3620 | No | ||
| 24 | CFL2 | 1418066_at 1418067_at 1431432_at | 16799 | -0.935 | -0.4781 | No | ||
| 25 | TRADD | 1429117_at 1439910_a_at 1452622_a_at | 16821 | -0.940 | -0.4704 | No | ||
| 26 | TOP1 | 1423474_at 1438495_at 1457573_at 1459672_at | 16915 | -0.960 | -0.4658 | No | ||
| 27 | BIRC3 | 1421392_a_at 1425223_at | 17574 | -1.109 | -0.4856 | No | ||
| 28 | APAF1 | 1450223_at | 18376 | -1.358 | -0.5096 | Yes | ||
| 29 | CASP9 | 1426125_a_at 1437537_at 1457816_at | 18419 | -1.374 | -0.4988 | Yes | ||
| 30 | GAS2 | 1429147_at 1435834_at 1438564_at 1450112_a_at | 18939 | -1.599 | -0.5077 | Yes | ||
| 31 | CASP2 | 1448165_at | 19003 | -1.624 | -0.4956 | Yes | ||
| 32 | GZMB | 1419060_at | 19425 | -1.811 | -0.4981 | Yes | ||
| 33 | BIRC2 | 1418854_at | 19444 | -1.821 | -0.4821 | Yes | ||
| 34 | PRF1 | 1451862_a_at | 19970 | -2.223 | -0.4855 | Yes | ||
| 35 | MAP3K1 | 1424850_at | 20648 | -2.888 | -0.4897 | Yes | ||
| 36 | SREBF1 | 1426690_a_at | 20907 | -3.287 | -0.4711 | Yes | ||
| 37 | ACTA1 | 1427735_a_at | 20946 | -3.379 | -0.4416 | Yes | ||
| 38 | DFFB | 1421229_at 1437051_at | 20947 | -3.380 | -0.4104 | Yes | ||
| 39 | ARHGDIB | 1426454_at | 21139 | -3.736 | -0.3845 | Yes | ||
| 40 | TRAF2 | 1451233_at | 21335 | -4.141 | -0.3552 | Yes | ||
| 41 | SATB1 | 1416007_at 1416008_at 1439203_at 1439449_at 1443284_at 1456902_at | 21342 | -4.159 | -0.3170 | Yes | ||
| 42 | TNFRSF1A | 1417291_at | 21839 | -8.146 | -0.2643 | Yes | ||
| 43 | CASP7 | 1426062_a_at 1448659_at | 21883 | -9.234 | -0.1809 | Yes | ||
| 44 | CASP6 | 1415995_at 1458715_at | 21892 | -9.592 | -0.0926 | Yes | ||
| 45 | DFFA | 1450885_at 1457564_at | 21915 | -10.213 | 0.0009 | Yes |
